Ozempic Babies: Weight-loss drugs may be causing unplanned pregnancies

Share on Pinterest
A growing number of people report becoming pregnant after using GLP-1 drugs like Ozempic, despite previous infertility or being on birth control pills. RealPeopleGroup/Getty Images
  • Women on TikTok report surprise pregnancies while using Ozempic.
  • This happens because GLP-1 drugs can interfere with the way birth control pills are absorbed.
  • Metabolic improvements due to weight loss may also play a role.
  • The manufacturer of Ozempic advises stopping this medication before conceiving.
  • Health experts say that if you become pregnant while using it, you should stop taking it immediately.

In a new trend that many have dubbed Ozempic babies, women are reporting on social media that they are getting pregnant after using GLP-1 drugs like Ozempic (semaglutide) to lose weight.

Some, like TikToker @fxshel1995, report getting pregnant after years of infertility.

In a response post, @dkalsolive shared that she was told she was infertile after her second c-section, but also became pregnant four months after starting Ozempic.

Others, like @haleyfriend11, responded to the post saying they got pregnant despite taking precautions.

I also got pregnant on Ozempic and was on the pill! He wrote the baby in June.

And while children conceived while using the drug are often called Ozempic babies, some expectant mothers, like @Chelsea, were also proclaiming success with other GLP-1 drugs.

She struggled with infertility for 8 years. She started Mounjaro, and 10 months later pregnant with our miracle baby, she commented.

So what’s going on with Ozempic’s baby boom? Are GLP-1 drugs somehow able to increase fertility? Or is something else going on?

Dr. Neha Lalani, a board-certified endocrinologist in private practice at Bluebonnet Diabetes & Endocrinology in West Lake Hills, Austin, Texas, confirmed that the phenomenon is definitely real.

We have seen cases of oral contraceptive failure as well as increased fertility with drugs such as GLP-1 agonists, he said.

As for the failure of birth control pills, Lalani said it has to do with how GLP-1 agonists work, as well as GLP/GLP-1 agonists.

These drugs slow down the emptying of the stomach, so they affect how food and medicine are absorbed.

This makes oral contraceptive pills not absorbed consistently, especially whenever the dose of GLP-1/GIP+ GLP-1 agonists is increased, he explained. This causes oral contraceptive pills to fail.

Lalani advises that people use alternative methods of birth control when using these medications.

As for direct effects on fertility, Lalani noted that more research is needed before we can say how GLP-1 agonists affect reproductive function.

However, Lalani speculated that the effect could be due to the fact that these drugs cause weight loss.

[I]Increased fertility and surprise pregnancy have been well reported in previously infertile patients, even with modest (approximately 5%) weight loss with lifestyle modifications as well as other medications for weight loss, he said.

Lalani added that improvements in metabolic health created by weight loss may be able to restore ovarian function.

Dr. Jamie Grifo, program director at NYU Langone Fertility Center in New York City and executive director of Inception Fertility, agreed with this assessment, saying: Many patients with a high BMI do not ovulate, some have syndrome d ‘polycystic ovary (PCOS) and many simply do not ovulate regularly.

With weight loss from these drugs, many women who are anovulatory begin to ovulate and menstruate regularly, bringing them from a low-fertility situation to a more normal fertile state, he explained.

There are serious risks to pregnancy when taking these drugs, and women should be watched very closely, especially if they are trying to get pregnant, Grifo added, explaining that a medical endocrinologist who specializes in weight loss, diabetes and endocrine. problems would be the best option to monitor your case.

Novo Nordisk, the maker of the Ozempic and Wegovy brands of semaglutide approved for the treatment of type 2 diabetes and obesity, respectively, provided Healthline with a statement saying that it is not currently known how safe these drugs are to use in pregnant people.

Those who were pregnant or trying to become pregnant were excluded from the semaglutide trials, so there are not enough human data available to establish whether semaglutide is associated with major birth defects, miscarriage, or adverse outcomes for the mother or the baby.

However, animal studies done with Wegovy suggest that there may be risks to using it.

A study on the safety of Wegovy in human pregnancy is ongoing and is not due to be completed until August 2027.

Currently, the prescribing information for Ozempic states that people should stop taking the drug for at least two months before becoming pregnant to allow enough time for the drug to be cleared from their bodies.

Wegovy provides a similar warning and further states that it can cause fetal harm and should be discontinued as soon as someone knows they are pregnant.

Individual patient decisions should be made together with a healthcare provider, as part of a shared decision-making process, the drugmaker advised.

Several people are taking to social media to report that they have become pregnant after using GLP-1 drugs like Ozempic sometimes after previous infertility or despite being on birth control pills.

Doctors say that GLP-1 drugs interfere with the absorption of birth control pills, making them less reliable.

The fact that weight loss improves metabolic health, which could help restore ovulation in infertile women, may also play a role.

It is not currently known whether GLP-1 drugs are safe during pregnancy. However, animal studies indicate that they could be harmful to the developing fetus.

It is recommended that people stop taking medications like Ozempic two months before trying to get pregnant.

If they become pregnant while using one of these medications, they should stop taking it immediately and consult a doctor.

#Ozempic #Babies #Weightloss #drugs #causing #unplanned #pregnancies
Image Source : www.healthline.com

Leave a Comment